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Kinetochore Dynein Is Required for Chromosome Motion and Congression Independent of the Spindle Checkpoint

During mitosis, the motor molecule cytoplasmic dynein plays key direct and indirect roles in organizing microtubules (MTs) into a functional spindle. At this time, dynein is also recruited to kinetochores, but its role or roles at these organelles remain vague, partly because inhibiting dynein globa...

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Detalhes bibliográficos
Main Authors: Yang, Zhenye, Tulu, U. Serdar, Wadsworth, Patricia, Rieder, Conly L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570756/
https://ncbi.nlm.nih.gov/pubmed/17509882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.04.056
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