Inhibition of human immunodeficiency virus (HIV-1) replication by synthetic oligo-RNA derivatives.

Several synthetic 2'-O-methyl-RNA oligomers and their derivatives have been evaluated for inhibitory effect against HIV-induced cytopathic effect and expression of the virus specific antigen in cultured MT-4 cells. In this study, oligo(2'-O-methyl)ribonucleoside phosphorothioates showed a...

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Auteurs principaux: Shibahara, S, Mukai, S, Morisawa, H, Nakashima, H, Kobayashi, S, Yamamoto, N
Format: Artigo
Langue:Inglês
Publié: 1989
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC331548/
https://ncbi.nlm.nih.gov/pubmed/2911465
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