Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs

Spliceosomes remove introns from primary gene transcripts. They assemble de novo on each intron through a series of steps that involve the incorporation of five snRNP particles and multiple non-snRNP proteins. In mammals, all the intermediate complexes have been characterized on one transcript (MINX...

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Bibliographic Details
Main Authors: Makarov, Evgeny M., Owen, Nicholas, Bottrill, Andrew, Makarova, Olga V.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315330/
https://ncbi.nlm.nih.gov/pubmed/22110043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1056
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