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The transition in spliceosome assembly from complex E to complex A purges surplus U1 snRNPs from alternative splice sites
Spliceosomes are assembled in stages. The first stage forms complex E, which is characterized by the presence of U1 snRNPs base-paired to the 5′ splice site, components recognizing the 3′ splice site and proteins thought to connect them. The splice sites are held in close proximity and the pre-mRNA...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413131/ https://ncbi.nlm.nih.gov/pubmed/22505580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks322 |
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