Enkephalin Elevations Contribute to Neuronal and Behavioral Impairments in a Transgenic Mouse Model of Alzheimer's Disease

The enkephalin signaling pathway regulates various neural functions and can be altered by neurodegenerative disorders. In Alzheimer's disease (AD), elevated enkephalin levels may reflect compensatory processes or contribute to cognitive impairments. To differentiate between these possibilities,...

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Detalhes bibliográficos
Main Authors: Meilandt, William J., Yu, Gui-Qiu, Chin, Jeannie, Roberson, Erik D., Palop, Jorge J., Wu, Tiffany, Scearce-Levie, Kimberly, Mucke, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315282/
https://ncbi.nlm.nih.gov/pubmed/18463254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0590-08.2008
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