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A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint

The COMA/CENP-H/I kinetochore complex regulates microtubule dynamics at kinetochores. The complex is also required to generate spindle checkpoint signals in both yeast and human cells under conditions where Aurora B activity is compromised. Our data explain why mammalian cells treated with Aurora in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matson, Daniel R., Demirel, Pinar B., Stukenberg, P. Todd, Burke, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315115/
https://ncbi.nlm.nih.gov/pubmed/22426531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.184184.111
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