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Linking kinetochore-microtubule binding to the spindle checkpoint

The spindle checkpoint blocks cell cycle progression until chromosomes are properly attached to the mitotic spindle. Popular models propose that checkpoint proteins associate with kinetochores to produce a “wait anaphase” signal that inhibits anaphase. Recent data suggests that a two-state switch re...

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Détails bibliographiques
Auteurs principaux: Burke, Daniel J., Stukenberg, P. Todd
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696048/
https://ncbi.nlm.nih.gov/pubmed/18410725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.03.015
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