Triple helix formation at distant sites: hybrid oligonucleotides containing a polymeric linker.

An oligonucleotide hybrid is described which possesses two triple helix forming oligonucleotides which have been connected by a flexible polymeric linker chain. As a prototype, binding of this class of oligonucleotide to duplex DNA has been studied using a segment of the HSV-1 D-glycoprotein promote...

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Bibliografiske detaljer
Main Authors: Kessler, D J, Pettitt, B M, Cheng, Y K, Smith, S R, Jayaraman, K, Vu, H M, Hogan, M E
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC331510/
https://ncbi.nlm.nih.gov/pubmed/8233830
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