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Oligonucleotide hybridizations on glass supports: a novel linker for oligonucleotide synthesis and hybridization properties of oligonucleotides synthesised in situ.

A novel linker for the synthesis of oligonucleotides on a glass support is described. Oligonucleotides synthesised on the support remain tethered to the support after ammonia treatment and are shown to take part in sequence specific hybridisation reactions. These hybridizations were carried out with...

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Detalhes bibliográficos
Main Authors: Maskos, U, Southern, E M
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312256/
https://ncbi.nlm.nih.gov/pubmed/1579459
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