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Autoregulation of kinase dephosphorylation by ATP binding to AGC protein kinases
AGC kinases, including the three Akt (protein kinase B) isoforms, protein kinase A (PKA) and all protein kinase C (PKC) isoforms, require activation loop phosphorylation (threonine 308 in Akt1) as well as phosphorylation of a C-terminal residue (serine 473 in Akt1) for catalytic activity and phospho...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315091/ https://ncbi.nlm.nih.gov/pubmed/22262182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.3.19059 |
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