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Binding of nucleic acids to E. coli RNase HI observed by NMR and CD spectroscopy.
To clarify the mechanism by which the RNA portion of a DNA/RNA hybrid is specifically hydrolyzed by ribonuclease H (RNase H), the binding of a DNA/RNA hybrid, a DNA/DNA duplex, or an RNA/RNA duplex to RNase HI from Escherichia coli was investigated by 1H-15N heteronuclear NMR. Chemical shift changes...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
1993
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| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC331492/ https://ncbi.nlm.nih.gov/pubmed/7694232 |
| Ετικέτες: |
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