Binding of nucleic acids to E. coli RNase HI observed by NMR and CD spectroscopy.
To clarify the mechanism by which the RNA portion of a DNA/RNA hybrid is specifically hydrolyzed by ribonuclease H (RNase H), the binding of a DNA/RNA hybrid, a DNA/DNA duplex, or an RNA/RNA duplex to RNase HI from Escherichia coli was investigated by 1H-15N heteronuclear NMR. Chemical shift changes...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1993
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7694232/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.20.4690 |
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