Hybridization specificity, enzymatic activity and biological (Ha-ras) activity of oligonucleotides containing 2,4-dideoxy-beta-D-erythro-hexopyranosyl nucleosides.

Antisense oligonucleotides with a 2,4-dideoxyhexopyranosyl nucleoside incorporated at the 3'-end and at a mutation site of the Ha-ras oncogene mRNA were synthesized. Melting temperature studies revealed that an A*-G mismatch is more stable than an A*-T mismatch with these hexopyranosyl nucleosi...

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Detaylı Bibliyografya
Asıl Yazarlar: Augustyns, K, Godard, G, Hendrix, C, Van Aerschot, A, Rozenski, J, Saison-Behmoaras, T, Herdewijn, P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1993
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC331489/
https://ncbi.nlm.nih.gov/pubmed/7694231
Etiketler: Etiketle
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