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How many strata in an RCT? A flexible approach

BACKGROUND: The need to allow for prognostic factors when designing and analysing cancer trials is well recognised, but the possibility of overstratification should be avoided by restricting the number of strata. The proposed method improves on existing guidance by being based on explicit principles...

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Autore principale: Silcocks, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314793/
https://ncbi.nlm.nih.gov/pubmed/22415237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.84
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