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How many strata in an RCT? A flexible approach

BACKGROUND: The need to allow for prognostic factors when designing and analysing cancer trials is well recognised, but the possibility of overstratification should be avoided by restricting the number of strata. The proposed method improves on existing guidance by being based on explicit principles...

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Autor principal: Silcocks, P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314793/
https://ncbi.nlm.nih.gov/pubmed/22415237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.84
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