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How many cases of disease in a pedigree imply familial disease?

The ability to perform whole‐exome and, increasingly, whole‐genome sequencing on large numbers of individuals has led to increased efforts to identify rare genetic variants that affect the risk of both common and rare diseases. In such applications, it is important to identify families that are segr...

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Detalhes bibliográficos
Publicado no:Ann Hum Genet
Main Authors: Dudbridge, Frank, Brown, Suzanne J., Ward, Lynley, Wilson, Scott G., Walsh, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813157/
https://ncbi.nlm.nih.gov/pubmed/29058319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12222
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