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Small Cationic DDA:TDB Liposomes as Protein Vaccine Adjuvants Obviate the Need for TLR Agonists in Inducing Cellular and Humoral Responses

Most subunit vaccines require adjuvants in order to induce protective immune responses to the targeted pathogen. However, many of the potent immunogenic adjuvants display unacceptable local or systemic reactogenicity. Liposomes are spherical vesicles consisting of single (unilamellar) or multiple (m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Milicic, Anita, Kaur, Randip, Reyes-Sandoval, Arturo, Tang, Choon-Kit, Honeycutt, Jared, Perrie, Yvonne, Hill, Adrian V. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314611/
https://ncbi.nlm.nih.gov/pubmed/22470545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034255
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