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Small Cationic DDA:TDB Liposomes as Protein Vaccine Adjuvants Obviate the Need for TLR Agonists in Inducing Cellular and Humoral Responses

Most subunit vaccines require adjuvants in order to induce protective immune responses to the targeted pathogen. However, many of the potent immunogenic adjuvants display unacceptable local or systemic reactogenicity. Liposomes are spherical vesicles consisting of single (unilamellar) or multiple (m...

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Detalhes bibliográficos
Main Authors: Milicic, Anita, Kaur, Randip, Reyes-Sandoval, Arturo, Tang, Choon-Kit, Honeycutt, Jared, Perrie, Yvonne, Hill, Adrian V. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314611/
https://ncbi.nlm.nih.gov/pubmed/22470545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034255
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