Synthesis of protein conjugates adsorbed on cationic liposomes surface

The well-known Toll like receptor 9 (TLR9) agonist CpG ODN has shown promising results as vaccine adjuvant in preclinical and clinical studies, however its in vivo • The CpG ODN Toll-like receptor (TLR) 9 agonist was conjugated to protein antigens via thiol-maleimide chemistry. • Due to their negati...

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Foilsithe in:MethodsX
Main Authors: Chatzikleanthous, Despo, Cunliffe, Robert, Carboni, Filippo, Romano, Maria Rosaria, O'Hagan, Derek T., Roberts, Craig W., Perrie, Yvonne, Adamo, Roberto
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2020
Ábhair:
Pharmacology, Toxicology and Pharmaceutical Science
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289768/
https://ncbi.nlm.nih.gov/pubmed/32551244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mex.2020.100942
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