Synthesis of protein conjugates adsorbed on cationic liposomes surface

The well-known Toll like receptor 9 (TLR9) agonist CpG ODN has shown promising results as vaccine adjuvant in preclinical and clinical studies, however its in vivo • The CpG ODN Toll-like receptor (TLR) 9 agonist was conjugated to protein antigens via thiol-maleimide chemistry. • Due to their negati...

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Gepubliceerd in:MethodsX
Hoofdauteurs: Chatzikleanthous, Despo, Cunliffe, Robert, Carboni, Filippo, Romano, Maria Rosaria, O'Hagan, Derek T., Roberts, Craig W., Perrie, Yvonne, Adamo, Roberto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
Onderwerpen:
Pharmacology, Toxicology and Pharmaceutical Science
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289768/
https://ncbi.nlm.nih.gov/pubmed/32551244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mex.2020.100942
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