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Conserved sequence motif DPPY in region IV of the phage T4 Dam DNA-[N(6)-adenine]-methyltransferase is important for S-adenosyl-L-methionine binding
Comparison of the deduced amino acid sequences of DNA-[N(6)-adenine]-methyltransferases has revealed several conserved regions. All of these enzymes contain a DPPY-motif, or a variant of it. By site-directed mutagenesis of a cloned T4 dam gene, we have altered the first proline residue in this motif...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1993
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC331459/ https://ncbi.nlm.nih.gov/pubmed/16617501 |
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