Conserved sequence motif DPPY in region IV of the phage T4 Dam DNA-[N(6)-adenine]-methyltransferase is important for S-adenosyl-L-methionine binding
Comparison of the deduced amino acid sequences of DNA-[N(6)-adenine]-methyltransferases has revealed several conserved regions. All of these enzymes contain a DPPY-motif, or a variant of it. By site-directed mutagenesis of a cloned T4 dam gene, we have altered the first proline residue in this motif...
Gardado en:
| Publicado en: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1993
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331459/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16617501/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.15.3563 |
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