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ANTI-AQUAPORIN-4 MONOCLONAL ANTIBODY BLOCKER THERAPY FOR NEUROMYELITIS OPTICA
OBJECTIVE: Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system. Circulating autoantibodies (NMO-IgG) against astrocyte water channel aquaporin-4 (AQP4) cause complement- and cell-mediated astrocyte damage with consequent neuroinflammation and demyelinati...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314396/ https://ncbi.nlm.nih.gov/pubmed/22271321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22657 |
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