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Interaction between the Cockayne syndrome B and p53 proteins: implications for aging

The CSB protein plays a role in the transcription coupled repair (TCR) branch of the nucleotide excision repair pathway. CSB is very often found mutated in Cockayne syndrome, a segmental progeroid genetic disease characterized by organ degeneration and growth failure. The tumor suppressor p53 plays...

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Detalhes bibliográficos
Main Authors: Frontini, Mattia, Proietti-De-Santis, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314171/
https://ncbi.nlm.nih.gov/pubmed/22383384
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