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Cockayne syndrome B protein regulates the transcriptional program after UV irradiation

The phenotype of the human genetic disorder Cockayne syndrome (CS) is not only due to DNA repair defect but also (and perhaps essentially) to a severe transcription initiation defect. After UV irradiation, even undamaged genes are not transcribed in CSB cells. Indeed, neither RNA pol II nor the asso...

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Detalhes bibliográficos
Main Authors: Proietti-De-Santis, Luca, Drané, Pascal, Egly, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456931/
https://ncbi.nlm.nih.gov/pubmed/16601682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601071
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