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Cockayne syndrome B protein regulates the transcriptional program after UV irradiation

The phenotype of the human genetic disorder Cockayne syndrome (CS) is not only due to DNA repair defect but also (and perhaps essentially) to a severe transcription initiation defect. After UV irradiation, even undamaged genes are not transcribed in CSB cells. Indeed, neither RNA pol II nor the asso...

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Autores principales: Proietti-De-Santis, Luca, Drané, Pascal, Egly, Jean-Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456931/
https://ncbi.nlm.nih.gov/pubmed/16601682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601071
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