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TACI-Fc gene therapy improves auto-immune sialadenitis but not salivary gland function in NOD mice
OBJECTIVE: Sjögren’s syndrome (SS) patients show aberrant expression of the B cell-related mediators B cell activating factor (BAFF) and a proliferation-inducing ligand (APRIL) in serum and salivary glands (SGs). We studied the biological effect of neutralizing these cytokines by local gene transfer...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314152/ https://ncbi.nlm.nih.gov/pubmed/22212434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-0825.2011.01885.x |
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