Effect of Soluble ICAM-1 on a Sjögren's Syndrome-like Phenotype in NOD Mice Is Disease Stage Dependent

INTRODUCTION: Intercellular adhesion molecule-1 (ICAM-1) is involved in migration and co-stimulation of T and B cells. Membrane bound ICAM-1 is over expressed in the salivary glands (SG) of Sjögren's syndrome (SS) patients and has therefore been proposed as a potential therapeutic target. To te...

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Bibliografiske detaljer
Main Authors: Roescher, Nienke, Vosters, Jelle L., Yin, Hongen, Illei, Gabor G., Tak, Paul P., Chiorini, John A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093404/
https://ncbi.nlm.nih.gov/pubmed/21589878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019962
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