Activation of Protein Kinase A and Exchange Protein Directly Activated by cAMP Promotes Adipocyte Differentiation of Human Mesenchymal Stem Cells

Human mesenchymal stem cells are primary multipotent cells capable of differentiating into several cell types including adipocytes when cultured under defined in vitro conditions. In the present study we investigated the role of cAMP signaling and its downstream effectors, protein kinase A (PKA) and...

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Autori principali: Jia, Bingbing, Madsen, Lise, Petersen, Rasmus Koefoed, Techer, Nathalie, Kopperud, Reidun, Ma, Tao, Døskeland, Stein Ove, Ailhaud, Gérard, Wang, Jinfu, Amri, Ez-Zoubir, Kristiansen, Karsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313974/
https://ncbi.nlm.nih.gov/pubmed/22479536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034114
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