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The Protein Partners of GTP Cyclohydrolase I in Rat Organs

OBJECTIVE: GTP cyclohydrolase I (GCH1) is the rate-limiting enzyme for tetrahydrobiopterin biosynthesis and has been shown to be a promising therapeutic target in ischemic heart disease, hypertension, atherosclerosis and diabetes. The endogenous GCH1-interacting partners have not been identified. He...

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Detalhes bibliográficos
Main Authors: Du, Jianhai, Teng, Ru-Jeng, Lawrence, Matt, Guan, Tongju, Xu, Hao, Ge, Ying, Shi, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313957/
https://ncbi.nlm.nih.gov/pubmed/22479495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033991
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