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On the viability of Escherichia coli cells lacking DNA topoisomerase I
BACKGROUND: Manipulations of the DNA double helix during replication, transcription and other nucleic acid processing cause a change of DNA topology, which results in torsional stress. This stress is relaxed by DNA topoisomerases, a class of enzymes present in all domains of life. Negatively superco...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3313902/ https://ncbi.nlm.nih.gov/pubmed/22373098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-12-26 |
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