Antineoplastic Agents. 548. Synthesis of Iodo- and Diiodocombstatin Phosphate Prodrugs()

Toward the objective of designing a structurally modified analogue of the combretastatin A-4 phosphate prodrug (1b) with the potential for increased specificity toward thyroid carcinoma, synthesis of a series of iodocombstatin phosphate (11a-h) and diiodocombstatin phosphate prodrugs (12a-h) has bee...

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Detalhes bibliográficos
Main Authors: Pettit, George R., Rosenberg, Heidi J., Dixon, Rachel, Knight, John C., Hamel, Ernest, Chapuis, Jean-Charles, Pettit, Robin K., Hogan, Fiona, Sumner, Brandy, Ain, Kenneth B., Trickey-Platt, Brindi
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313684/
https://ncbi.nlm.nih.gov/pubmed/22324723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np200797x
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