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Antineoplastic Agents 515. Synthesis of Human Cancer Cell Growth Inhibitors Derived From 3,4-Methylenedioxy-5,4′-dimethoxy-3′-amino-Z-stilbene

Further structure-activity relationship (SAR) exploration of 3,4-methylenedioxy-5,4′-dimethoxy-3′-amino-Z-stilbene (1a) derivatives resulted in the efficient synthesis of tyrosine amide hydrochloride 9, two tyrosine amide phosphate prodrugs (3a and 6), and sodium aspartate amide 11. Two additional c...

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Main Authors: Pettit, George R., Anderson, Collin R., Gapud, Eric J., Jung, M. Katherine, Knight, John C., Hamel, Ernest, Pettit, Robin K.
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335365/
https://ncbi.nlm.nih.gov/pubmed/16124759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np058033l
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