Azalysine Analogs as Probes for Protein Lysine Deacetylation and Demethylation

Reversible lysine acetylation and methylation regulate the function of a wide variety of proteins, including histones. Here we have synthesized azalysine-containing peptides in acetylated and unacetylated forms as chemical probes of the histone deacetylases (HDAC8, Sir2Tm, and SIRT1) and the histone...

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Bibliografische gegevens
Hoofdauteurs: Dancy, Blair C. R., Ming, Shonoi A., Papazyan, Romeo, Jelinek, Christine A., Majumdar, Ananya, Sun, Yan, Dancy, Beverley M., Drury, William J., Cotter, Robert J., Taverna, Sean D., Cole, Philip A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313494/
https://ncbi.nlm.nih.gov/pubmed/22352831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja209574z
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