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Zhx2 and Zbtb20: Novel regulators of postnatal alpha-fetoprotein repression and their potential role in gene reactivation during liver cancer

The mouse alpha-fetoprotein (AFP) gene is abundantly expressed in the fetal liver, normally silent in the adult liver but is frequently reactivated in hepatocellular carcinoma. The basis for AFP expression in the fetal liver has been studied extensively. However, the basis for AFP reactivation durin...

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Autors principals: Peterson, Martha L., Ma, Chunhong, Spear, Brett T.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313486/
https://ncbi.nlm.nih.gov/pubmed/21216289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2011.01.001
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