ROLIPRAM: A SPECIFIC PHOSPHODIESTERASE 4 INHIBITOR WITH POTENTIAL ANTIPSYCHOTIC ACTIVITY

Currently available antipsychotic medications work primarily by antagonizing D(2) dopamine receptors, thus raising intracellular cAMP levels. We hypothesized that intracellular stimulation of cAMP levels in the CNS would have similar effects to treatment with antipsychotic medication. To test this h...

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Hauptverfasser: Kanes, S. J., Tokarczyk, J., Siegel, S. J., Bilker, W., Abel, T., Kelly, M. P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313447/
https://ncbi.nlm.nih.gov/pubmed/17081698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2006.09.026
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