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ROLIPRAM: A SPECIFIC PHOSPHODIESTERASE 4 INHIBITOR WITH POTENTIAL ANTIPSYCHOTIC ACTIVITY

Currently available antipsychotic medications work primarily by antagonizing D(2) dopamine receptors, thus raising intracellular cAMP levels. We hypothesized that intracellular stimulation of cAMP levels in the CNS would have similar effects to treatment with antipsychotic medication. To test this h...

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Detalhes bibliográficos
Main Authors: Kanes, S. J., Tokarczyk, J., Siegel, S. J., Bilker, W., Abel, T., Kelly, M. P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313447/
https://ncbi.nlm.nih.gov/pubmed/17081698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2006.09.026
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