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Mapping the Growth Hormone – Stat5b – IGF-I Transcriptional Circuit
Growth hormone (GH) and insulin-like growth factor-I (IGF-I) exert powerful influences on somatic growth, metabolism, and tissue repair, and have been implicated in aging and carcinogenesis. Since the formulation of the somatomedin hypothesis over 50 years ago, GH and IGF-I have been linked intimate...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3313013/ https://ncbi.nlm.nih.gov/pubmed/22361342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2012.01.001 |
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