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Dispersed Chromosomal Stat5b-binding Elements Mediate Growth Hormone-activated Insulin-like Growth Factor-I Gene Transcription

The growth hormone (GH)-insulin-like growth factor-I (IGF-I) axis regulates somatic growth during childhood and orchestrates tissue repair throughout the life span. Recently described inactivating mutations in Stat5b in humans with impaired growth have focused attention on this transcription factor...

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Autori principali: Chia, Dennis J., Varco-Merth, Ben, Rotwein, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878528/
https://ncbi.nlm.nih.gov/pubmed/20378540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.117697
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