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Dispersed Chromosomal Stat5b-binding Elements Mediate Growth Hormone-activated Insulin-like Growth Factor-I Gene Transcription

The growth hormone (GH)-insulin-like growth factor-I (IGF-I) axis regulates somatic growth during childhood and orchestrates tissue repair throughout the life span. Recently described inactivating mutations in Stat5b in humans with impaired growth have focused attention on this transcription factor...

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Detalhes bibliográficos
Main Authors: Chia, Dennis J., Varco-Merth, Ben, Rotwein, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878528/
https://ncbi.nlm.nih.gov/pubmed/20378540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.117697
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