Interaction Analysis between HLA-DRB1 Shared Epitope Alleles and MHC Class II Transactivator CIITA Gene with Regard to Risk of Rheumatoid Arthritis

HLA-DRB1 shared epitope (SE) alleles are the strongest genetic determinants for autoantibody positive rheumatoid arthritis (RA). One of the key regulators in expression of HLA class II receptors is MHC class II transactivator (CIITA). A variant of the CIITA gene has been found to associate with infl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ronninger, Marcus, Seddighzadeh, Maria, Eike, Morten Christoph, Plant, Darren, Daha, Nina A., Skinningsrud, Beate, Worthington, Jane, Kvien, Tore K., Toes, Rene E. M., Lie, Benedicte A., Alfredsson, Lars, Padyukov, Leonid
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312880/
https://ncbi.nlm.nih.gov/pubmed/22461888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032861
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