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Central B-Cell Tolerance: Where Selection Begins
The development of an adaptive immune system based on the random generation of antigen receptors requires a stringent selection process that sifts through receptor specificities to remove those reacting with self-antigens. In the B-cell lineage, this selection process is first applied to IgM(+) imma...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312675/ https://ncbi.nlm.nih.gov/pubmed/22378602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a007146 |
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