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Central B-Cell Tolerance: Where Selection Begins

The development of an adaptive immune system based on the random generation of antigen receptors requires a stringent selection process that sifts through receptor specificities to remove those reacting with self-antigens. In the B-cell lineage, this selection process is first applied to IgM(+) imma...

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Autors principals: Pelanda, Roberta, Torres, Raul M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312675/
https://ncbi.nlm.nih.gov/pubmed/22378602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a007146
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