SYNERGISTIC EFFECT OF NOREPINEPHRINE TRANSPORTER BLOCKADE AND ALPHA-2 ANTAGONISM ON BLOOD PRESSURE IN AUTONOMIC FAILURE

Patients with autonomic failure have disabling orthostatic hypotension due to impaired sympathetic activity. Norepinephrine transporter (NET) blockade with atomoxetine raises blood pressure in autonomic failure by increasing synaptic norepinephrine concentrations in postganglionic sympathetic neuron...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Okamoto, Luis E., Shibao, Cyndya, Gamboa, Alfredo, Choi, Leena, Diedrich, André, Raj, Satish R., Black, Bonnie K., Robertson, David, Biaggioni, Italo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312003/
https://ncbi.nlm.nih.gov/pubmed/22311903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.184812
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