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SYNERGISTIC EFFECT OF NOREPINEPHRINE TRANSPORTER BLOCKADE AND ALPHA-2 ANTAGONISM ON BLOOD PRESSURE IN AUTONOMIC FAILURE
Patients with autonomic failure have disabling orthostatic hypotension due to impaired sympathetic activity. Norepinephrine transporter (NET) blockade with atomoxetine raises blood pressure in autonomic failure by increasing synaptic norepinephrine concentrations in postganglionic sympathetic neuron...
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| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312003/ https://ncbi.nlm.nih.gov/pubmed/22311903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.184812 |
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