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Kinetic Analysis of PI3K Reactions with Fluorescent PIP(2) Derivatives

PI3K signaling plays important roles in cell differentiation, proliferation, and migration. Increased mutations and expression levels of PI3K are hallmarks for the development of certain cancers. Pharmacological targeting of PI3K activity has also been actively pursued as a novel cancer therapeutic....

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Hlavní autoři: Huang, Weigang, Jiang, Dechen, Wang, Xiaoyang, Wang, Kelong, Sims, Christopher E., Allbritton, Nancy L., Zhang, Qisheng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311999/
https://ncbi.nlm.nih.gov/pubmed/21789487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-011-5257-z
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