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Kinetic Analysis of PI3K Reactions with Fluorescent PIP(2) Derivatives

PI3K signaling plays important roles in cell differentiation, proliferation, and migration. Increased mutations and expression levels of PI3K are hallmarks for the development of certain cancers. Pharmacological targeting of PI3K activity has also been actively pursued as a novel cancer therapeutic....

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Detalhes bibliográficos
Main Authors: Huang, Weigang, Jiang, Dechen, Wang, Xiaoyang, Wang, Kelong, Sims, Christopher E., Allbritton, Nancy L., Zhang, Qisheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311999/
https://ncbi.nlm.nih.gov/pubmed/21789487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-011-5257-z
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