Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia

It is generally accepted that the intercalated disc (ICD) required for mechano-electrical coupling in the heart consists of three distinct junctional complexes: adherens junctions, desmosomes and gap junctions. However, recent morphological and molecular data indicate a mixing of adherens junctional...

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Autori principali: Li, Jifen, Goossens, Steven, van Hengel, Jolanda, Gao, Erhe, Cheng, Lan, Tyberghein, Koen, Shang, Xiying, De Rycke, Riet, van Roy, Frans, Radice, Glenn L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2012
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311935/
https://ncbi.nlm.nih.gov/pubmed/22421363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.098640
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