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Alpha-Catenins Control Cardiomyocyte Proliferation by Regulating Yap Activity

RATIONALE: Shortly after birth, muscle cells of the mammalian heart lose their ability to divide. Thus, they are unable to effectively replace dying cells in the injured heart. The recent discovery that the transcriptional co-activator Yap is necessary and sufficient for cardiomyocyte proliferation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Circ Res
Hauptverfasser: Li, Jifen, Gao, Erhe, Vite, Alexia, Yi, Roslyn, Gomez, Ludovic, Goossens, Steven, van Roy, Frans, Radice, Glenn L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282606/
https://ncbi.nlm.nih.gov/pubmed/25305307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.304472
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