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Loss of Cadherin-Binding Proteins β-Catenin and Plakoglobin in the Heart Leads to Gap Junction Remodeling and Arrhythmogenesis

Arrhythmic right ventricular cardiomyopathy (ARVC) is a hereditary heart muscle disease that causes sudden cardiac death (SCD) in young people. Almost half of ARVC patients have a mutation in genes encoding cell adhesion proteins of the desmosome, including plakoglobin (JUP). We previously reported...

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Detalhes bibliográficos
Main Authors: Swope, David, Cheng, Lan, Gao, Erhe, Li, Jifen, Radice, Glenn L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295003/
https://ncbi.nlm.nih.gov/pubmed/22252313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06188-11
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