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N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility

Cardiac-specific deletion of the murine gene (Cdh2) encoding the cell adhesion molecule, N-cadherin, results in disassembly of the intercalated disc (ICD) structure and sudden arrhythmic death. Connexin 43 (Cx43)-containing gap junctions are significantly reduced in the heart after depleting N-cadhe...

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Bibliografski detalji
Glavni autori: Li, Jifen, Levin, Mark D, Xiong, Yanming, Petrenko, Nataliya, Patel, Vickas V., Radice, Glenn L.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2314673/
https://ncbi.nlm.nih.gov/pubmed/18201716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.11.013
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