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N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility
Cardiac-specific deletion of the murine gene (Cdh2) encoding the cell adhesion molecule, N-cadherin, results in disassembly of the intercalated disc (ICD) structure and sudden arrhythmic death. Connexin 43 (Cx43)-containing gap junctions are significantly reduced in the heart after depleting N-cadhe...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2314673/ https://ncbi.nlm.nih.gov/pubmed/18201716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.11.013 |
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